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Challenges in interpreting cytokine data in COVID-19 affect patient care and management.
Wang, Stephen Y; Takahashi, Takehiro; Pine, Alexander B; Damsky, William E; Simonov, Michael; Zhang, Yanhua; Kieras, Elizabeth; Price, Christina C; King, Brett A; Siegel, Mark D; Desir, Gary V; Lee, Alfred I; Iwasaki, Akiko; Chun, Hyung J.
PLoS Biol ; 19(8): e3001373, 2021 08.
Article in English | MEDLINE | ID: covidwho-1346324

ABSTRACT

Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experience gained during the COVID-19 pandemic.


Subject(s)
COVID-19/immunology , COVID-19/therapy , COVID-19/epidemiology , Cytokines/immunology , Humans , Pandemics , Patient Care/methods , SARS-CoV-2/immunology
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